NeuroGen Brain and Spine Institute is not just an organization, but a collective, committed concept, of paving the way to a brighter future, and a life of independence, for individuals with incurable neurological disorders, through the combination of revolutionary regenerative medicine, holistic comprehensive neurorehabilitation and medical intervention.
Some time ago donated organs were transplanted to replace the diseased or failed organs in the recipients. Soon the number of recipients exceeded the number of donated. To overcome this demand, cell therapy offered the possibility of replacement of the damaged cells of tissue with new cells. Stem cell infusion helps to treat a plethora of conditions including cerebral palsy, spinal cord injury, intellectual disability, and other neurodegenerative syndromes as well.
Stem cells have the potential to develop into different cells of the tissues (of the body) and the ability of self-renewal. When serving as a repair system, the stem cells divide without limit as long as the person is alive. As they divide, they remain as stem cells or develop into cells with more specialized functions, like a brain cell or a muscle cell.
Stem cells, from different sources, have three common properties: They can grow into specialized cell types such as nerve cells, muscle cells, and blood cells.
Impairments linked to neuromuscular conditions are usually irreversible due to inadequate cell regeneration or impaired cells in the central nervous system. It was observed that the cellular characteristics of autologous stem cells had the capability of treating major neurological disorders without incurring any side effects. With their neurotrophic properties, self-renewal & differentiation capacity, and immune modulation effects, the bone marrow-derived stem cells are considered as a promising candidate for treating disorders related to the nervous system.
For cell treatment, bone marrow derived mesenchymal stem cells are isolated from the marrow tissue (extracted from the patient’s hip bone) in an expedited, painless and safe way. By centrifugation procedure, a sufficient number of stem cells are separated from the unwanted tissue within a few hours. These injectable stem cells are infused intrathecally into the spinal area or the damaged muscle points, as per the need of the patients.
These bone marrow-derived stem cells have many useful properties that lead to great clinical improvement in post-cell-based therapy. According to various clinical trials, treatment with bone marrow derived mesenchymal stem cells have shown improvement in patients with traumatic brain injury, spinal cord injury and other neurological disorders through axonal sprouting and remyelination, potential to replace/protect the damaged neurons/cells, and neovascularization.
How do the infused stem cells act? Once infused into the body,
– The infused stem cells journey toward the nervous system and blend into the neural circuits to mend or improve the disrupted synaptic transmission.
– Post infusion, improved neuropathological condition, upregulated Aß clearance and reduced deposition is detected within a short period.
– The infused stem cells reduce neuroinflammation and provide protective immunomodulatory effect.
– The stem cells secrete neurotrophic influence and nerve growth factors, bringing cognitive and memory improvement in patients.
Apart from encouraging effects, renewed brain plasticity is also observed in patients following intrathecal delivery of stem cells. With the new medical breakthrough in stem cell therapy, the treatment has become a highly sought-after curative. To know about the treatment efficacy, one must understand the efficiency of stem cells in terms of engraftment, migration, cytokines and growth factors. However, cell-based therapy is a promising contribution to regenerative medicine and has gained considerable clinical attention. Read more details at NeuroGen Hospital.
Considerations Before Starting Treatment: The needs of a child with cerebral palsy aren’t solely based on correcting their physical disabilities. There are also social and emotional aspects of living a more fulfilling life. These aspects shouldn’t be ignored when considering treatment and therapy. Many children are content with their disabilities. As a parent, it’s important to consider their feelings. Some treatments can be stressful and uncomfortable, and may not be in the best interest of the child. It’s important to discuss the physical and emotional impacts of all treatments with specialists and most importantly, the child.
A few tricks to help your child with autism: Keep in mind that no matter what treatment plan is chosen, your involvement is vital to success. You can help your child get the most out of treatment by working hand-in-hand with the treatment team and following through with the therapy at home. (This is why your well-being is essential!) When it comes to autism treatment, there are a dizzying variety of therapies and approaches. Some autism therapies focus on reducing problematic behaviors and building communication and social skills, while others deal with sensory integration problems, motor skills, emotional issues, and food sensitivities. With so many choices, it is extremely important to do your research, talk to autism treatment experts, and ask questions. But keep in mind that you don’t have to choose just one type of therapy. The goal of autism treatment should be to treat your child’s unique array of symptoms and needs. This often requires a combined treatment approach that incorporates several different types of therapy.
The spinal cord is responsible for sending messages from the brain to all parts of the body. It also sends messages from the body to the brain. We’re able to perceive pain and move our limbs because of messages sent through the spinal cord. If the spinal cord sustains an injury, some or all of these impulses may not be able to “get through.” The result is a complete or total loss of sensation and mobility below the injury. A spinal cord injury closer to the neck will typically cause paralysis throughout a larger part of the body than one in the lower back area.
US researchers are now trying to find a way to use stem cells for patients with paralysis or brain injury, for patients with type 1 diabetes, those with spinal cord injury, heart disease, people who have a heart attack or disorder neurological disorders such as multiple sclerosis. Many of the studies have been carried out on animals, and the results are in an early stage. It is important to note that the treatment with stem cells is not done with the patient’s own stem cells, because this is how the premises of the disease return are created. However, there were exceptions, proof stands a case from 2007, published in the journal Pediatric, of a child who was ill with leukemia and who was transplanted his own stem cells harvested at birth, following that 5 years after the intervention, the child to be completely healthy. Instead, it is indicated that the stem cell donors are the patient’s brother or sister. But in only 25% of cases it is shown that the brother is compatible with the patient, and 7 out of 10 patients must seek a donor outside the family.
Stem cell therapy is the finest medical breakthrough in history. It has bagged the much acclaimed ‘Nobel Prize in Medicine’ in the year 2012. This miracle discovery, Stem Cell therapy, has leveraged and firmly positioned India in the field of medical science, worldwide. Stem cell therapy has changed the medical perception of ‘incurable neurological disorders’ and has broken all shackles. Regenerative medicine or stem cell therapy is one of the most promising branches of advanced medication. Its main objective is to restore organ and tissue function for patients with continual and persistent diseases. Over the years, scientists and surgeons have been using stem cell therapy to renew and repair tissues affected with age, disease and congenital defects. Read more details on Stem Cell Therapy.